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Chemical compound
Ro07-5220 (6'-Chlorodiclazepam) is a benzodiazepine derivative with sedative, anxiolytic, anticonvulsant and muscle relaxant effects,[1][2][3] which has been sold as a designer drug.[4]
See also
References
- ^ Fryer RI, Leimgruber W, Trybulski EJ (September 1982). "Quinazolines and 1,4-benzodiazepines. 90. Structure-activity relationship between substituted 2-amino-N-(2-benzoyl-4-chlorophenyl)acetamides and 1,4-benzodiazepinones". Journal of Medicinal Chemistry. 25 (9): 1050–5. doi:10.1021/jm00351a009. PMID 6127410.
- ^ Maddalena DJ, Johnston GA (February 1995). "Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABAA receptors using artificial neural networks". Journal of Medicinal Chemistry. 38 (4): 715–24. doi:10.1021/jm00004a017. PMID 7861419.
- ^ Richter L, de Graaf C, Sieghart W, Varagic Z, Mörzinger M, de Esch IJ, Ecker GF, Ernst M (March 2012). "Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands". Nature Chemical Biology. 8 (5): 455–64. doi:10.1038/nchembio.917. PMC 3368153. PMID 22446838.
- ^ Catalani V, Botha M, Corkery JM, Guirguis A, Vento A, Scherbaum N, Schifano F (July 2021). "The Psychonauts' Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity". Pharmaceuticals (Basel, Switzerland). 14 (8): 720. doi:10.3390/ph14080720. PMC 8398354. PMID 34451817.
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Barbiturates |
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Benzodiazepines |
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Carbamates | |
Flavonoids |
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Imidazoles | |
Kava constituents | |
Monoureides | |
Neuroactive steroids |
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Nonbenzodiazepines | |
Phenols | |
Piperidinediones | |
Pyrazolopyridines | |
Quinazolinones | |
Volatiles/gases |
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Others/unsorted |
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