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Chemical compound
Further information: Racecadotril
Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1][2]
References
- ^ a b Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology. 125 (1): 147–50. doi:10.1016/0014-2999(86)90094-4. PMID 3015640.
- ^ Matheson AJ, Noble S (April 2000). "Racecadotril". Drugs. 59 (4): 829–35, discussion 836–7. doi:10.2165/00003495-200059040-00010. PMID 10804038. S2CID 245710392.
Rehydration | |
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Intestinal anti-infectives | |
Intestinal adsorbents |
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Antipropulsives (opioids) |
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Intestinal anti-inflammatory agents |
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Antidiarrheal micro-organisms | |
Other antidiarrheals | |
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