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Monoclonal antibody
Fasinumab is a human monoclonal antibody designed for the treatment of acute sciatic pain.[1][2]
This drug was developed in collaboration by Teva Pharmaceutical Industries and Regeneron Pharmaceuticals.
It is currently at Phase III trials (NCT03245008, NCT02683239, and NCT03161093).[3]
See also
References
- ^ "Fasinumab" (PDF). Statement On A Nonproprietary Name Adopted By The USAN Council. American Medical Association.
- ^ Tiseo PJ, Ren H, Mellis S (2014). "Fasinumab (REGN475), an antinerve growth factor monoclonal antibody, for the treatment of acute sciatic pain: results of a proof-of-concept study". Journal of Pain Research. 7: 523–530. doi:10.2147/JPR.S65974. PMC 4155988. PMID 25210473.
- ^ Oo WM, Hunter DJ (November 2021). "Nerve Growth Factor (NGF) Inhibitors and Related Agents for Chronic Musculoskeletal Pain: A Comprehensive Review". BioDrugs. 35 (6): 611–641. doi:10.1007/s40259-021-00504-8. PMID 34807432. S2CID 244509341.
Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems | |||||||||
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Bone |
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Musculoskeletal |
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Circulatory |
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Neurologic |
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Angiogenesis inhibitor |
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Growth factor |
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