Vitis

In enzymology, a mannose-1-phosphate guanylyltransferase (GDP) (EC 2.7.7.22) is an enzyme that catalyzes the chemical reaction

GDP + alpha-D-mannose 1-phosphate phosphate + GDP-mannose

Thus, the two substrates of this enzyme are GDP and alpha-D-mannose 1-phosphate, whereas its two products are phosphate and GDP-mannose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GDP:alpha-D-mannose-1-phosphate guanylyltransferase. This enzyme participates in fructose and mannose metabolism.

Other common names

• GDP mannose phosphorylase
• Mannose 1-phosphate (guanosine diphosphate) guanylyltransferase
• GDP mannose phosphorylase
• GDP-mannose 1-phosphate guanylyltransferase
• Guanosine diphosphate-mannose 1-phosphate guanylyltransferase
• Guanosine diphosphomannose phosphorylase
• Mannose 1-phosphate guanylyltransferase
• GDP:D-mannose-1-phosphate guanylyltransferase

References

• CARMINATTI H, CABIB E (1961). "Phosphorolysis of the pyrophosphate bond of some nucleotides". Biochim. Biophys. Acta. 53 (2): 417–9. doi:10.1016/0006-3002(61)90458-9. PMID 13876695.