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Chemical compound
TRPV3-74a is a drug which acts as a selective antagonist for the TRPV3 calcium channel. It has analgesic effects in animal studies against both neuropathic pain and normal pain responses.[1][2]
References
- ^ Gomtsyan A, Schmidt RG, Bayburt EK, Gfesser GA, Voight EA, Daanen JF, et al. (May 2016). "Synthesis and Pharmacology of (Pyridin-2-yl)methanol Derivatives as Novel and Selective Transient Receptor Potential Vanilloid 3 Antagonists". Journal of Medicinal Chemistry. 59 (10): 4926–47. doi:10.1021/acs.jmedchem.6b00287. PMID 27077528.
- ^ Kocienski P (February 2017). "Synthesis of a TRPV3 Antagonist". Synfacts. 13 (2): 123. doi:10.1055/s-0036-1589889. S2CID 100058677.
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