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MLS, or Major League Soccer, is a men's professional soccer league in the United States and Canada.
MLS may also refer to:
Academic degrees
- Master of Arts in Liberal Studies or Master of Liberal Studies
- Master of Library and Information Science or Master of Library Science, US and Canada
- Master of Studies in Law or Master of Legal Studies
Computer technology
- Maximum length sequence, a type of pseudorandom binary sequence
- MLS (Making Life Simple) S.A., a Greek software and telecommunications company
- Messaging Layer Security, encryption protocol
- Mozilla Location Service, a geolocation service
- Multilayer switch, in computer networking
- Multilevel security
Other
- Maritime Launch Services, a Canadian space transport services company
- Martin-Luther-Schule, a secondary school
- Medical laboratory scientist
- Michigan Lutheran Seminary
- Microwave landing system, a radio guidance system
- Microwave limb sounders, measuring microwave emission from Earth's upper atmosphere
- Multi-layer steel, a type of automotive head gasket
- Multiple listing service of real estate brokers
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