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Pinaverium bromide (INN) is a medication used for functional gastrointestinal disorders. It belongs to a drug group called antispasmodics and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.[1]

Pinaverium bromide was first registered in 1975 by Solvay Pharmaceuticals (now a division of Abbott Laboratories), and marketed globally using the brand names Dicetel and Eldicet. Generic pinaverium is available in South Korea under a trade name of Disten[2] and in Argentina as Nulite.[3]

Indications

It is indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS) including abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.[4]

References

  1. ^ "Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines [Internet].". CADTH Rapid Response Reports. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health. November 2015. PMID 26985535.
  2. ^ "Drug/Drug Information: Disten Tablet". KMLE (in Korean).
  3. ^ "NULITE". Laboratorio Dominguez.
  4. ^ Abbott Laboratories (Feb 2012). Dicetel Product Insert/Information Malaysia.
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