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Hydrocodone/homatropine, sold under the brand name Tussigon among others, is a fixed-dose combination medication used for the treatment of cough.[1][2] It contains hydrocodone, as the bitartrate, an opioid agonist; and homatropine, as the methylbromide, a muscarinic antagonist.[1][2] It is taken by mouth.[1][2]

Hydrocodone/homatropine was approved for medical use in the United States in 1943.[1][2]

Adverse effects

In the US, the label for hydrocodone/homatropine contains a black box warning about addiction, abuse, and misuse.[1][2]

References


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