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Moselle is a river in France, Luxembourg and Germany.

Moselle may also refer to:

• Moselle (department), French département surrounding the river
• Moselle (riverboat), American 19th-century riverboat
• Moselle wine from the region around the river
• River Moselle (London), England
• Moselle, Mississippi, unincorporated community in the United States
• Moselle, Missouri, unincorporated community in the United States
• Mosel, Wisconsin, township in the United States, sometimes spelled Moselle and named after the river
  • Mosel, Wisconsin, unincorporated community in the above township
• Open de Moselle, ATP tennis tournament

People with the surname

• Tyler Moselle, American academic

See also

• Mosel (disambiguation)
• Mozelle (disambiguation)