Rheum

by | Mar 21, 2018 | Rheum

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Rhaponticin is a stilbenoid glucoside compound. Its aglycone is called rhapontigenin. It can be found in rhubarb rhizomes.[1]

It has beneficial effects on diabetic mice,[1] and in vitro results suggest it may be relevant to Alzheimer's disease with an action on beta amyloid.[2] It is a phytoestrogen and has estrogenic activity.[3][4]

References

  1. ^ a b Chen, Jinlong; Ma, Mengmeng; Lu, Yanwei; Wang, Lisheng; Wu, Chutse; Duan, Haifeng (2009). "Rhaponticin from Rhubarb Rhizomes Alleviates Liver Steatosis and Improves Blood Glucose and Lipid Profiles in KK/Ay Diabetic Mice". Planta Medica. 75 (5): 472–7. doi:10.1055/s-0029-1185304. PMID 19235684.
  2. ^ Misiti, F; Sampaolese, B; Mezzogori, D; Orsini, F; Pezzotti, M; Giardina, B; Clementi, M (2006). "Protective effect of rhubarb derivatives on amyloid beta (1–42) peptide-induced apoptosis in IMR-32 cells: A case of nutrigenomic". Brain Research Bulletin. 71 (1–3): 29–36. doi:10.1016/j.brainresbull.2006.07.012. PMID 17113925. S2CID 31748806.
  3. ^ Nirali Prakashan (2009). Pharmacognosy. Nirali Prakashan. pp. 8–. ISBN 978-81-963961-5-2.
  4. ^ Andrea R. Genazzani; Basil C. Tarlatzis (1 December 2015). Frontiers in Gynecological Endocrinology: Volume 3: Ovarian Function and Reproduction - From Needs to Possibilities. Springer. pp. 178–. ISBN 978-3-319-23865-4.


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