Purple Passionflower – Passiflora incarnata

by | Dec 19, 2023 | Purple Passionflower

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ZM-182345 is a nonsteroidal progestin that was never marketed.[1][2] It was derived from structural modification of the nonsteroidal antiandrogen hydroxyflutamide.[1][2] ZM-182345 was found to be at least as potent as progesterone as a progestogen in animals but to also possess androgenic activity.[1]

References

  1. ^ a b c Dukes M, Furr BJ, Hughes LR, Tucker H, Woodburn JR (2000). "Nonsteroidal progestins and antiprogestins related to flutamide". Steroids. 65 (10–11): 725–31. doi:10.1016/s0039-128x(00)00179-3. PMID 11108883. S2CID 9749394.
  2. ^ a b Schöllkopf K, Schmees N (8 September 2008). "Progesterone receptor: overview of modern steroidal progestins and developments in the field of nonsteroidal selective progesterone receptor modulators.". In Ottow E, Weinmann H (eds.). Nuclear Receptors as Drug Targets. John Wiley & Sons. pp. 209–. ISBN 978-3-527-62330-3.



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