Penstemon

by | Mar 21, 2018 | Penstemon

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Drupanol is a naturally occurring phenol that has been isolated from the seeds of Psoralea drupaceae.[1][2] Although drupanol is sometimes said to be the same compound as bakuchiol, the two compounds are in fact distinct; they have the same molecular formula and weight but different chemical structures and hence are structural isomers.[1] Bakuchiol has been found to possess antiandrogenic activity in vitro.[3]

References

  1. ^ a b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 120,473. ISBN 978-1-4757-2085-3.
  2. ^ Golovina LA, Nikonov GK (1973). "The structure of drupanol — A new phenol from Psoralea drupaceae". Chemistry of Natural Compounds. 9 (1): 7–9. doi:10.1007/BF00580876. ISSN 0009-3130. S2CID 4813778.
  3. ^ Miao L, Ma SW, Fan GW, Wang H, Wang YF, Chai LJ (2013). "Bakuchiol inhibits the androgen induced-proliferation of prostate cancer cell line LNCaP through suppression of AR transcription activity". Tianjin Journal of Traditional Chinese Medicine. 5: 012.


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