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Ribulose is a ketopentose — a monosaccharide containing five carbon atoms, and including a ketone functional group. It has chemical formula C5H10O5. Two enantiomers are possible, d-ribulose (d-erythro-pentulose) and l-ribulose (l-erythro-pentulose). d-Ribulose is the diastereomer of d-xylulose.

Ribulose sugars are composed in the pentose phosphate pathway from arabinose.[1] They are important in the formation of many bioactive substances. For example, d-ribulose is an intermediate in the fungal pathway for d-arabitol production. Also, as the 1,5-bisphosphate, d-ribulose combines with carbon dioxide at the start of the photosynthesis process in green plants (carbon dioxide trap).[2]

Ribulose has the same stereochemistry at carbons 3 and 4 as the five-carbon aldoses ribose and arabinose.

References

  1. ^ Guo, Zongren; Long, Liangkun; Ding, Shaojun (2020). "Characterization of an L-Arabinose Isomerase from Bacillus velezensis and Its Application for L-Ribulose and L-Ribose Biosynthesis". Applied Biochemistry and Biotechnology. 192 (3): 935–951. doi:10.1007/s12010-020-03380-0. PMID 32617845. S2CID 220296031.
  2. ^ Spreitzer, Robert J.; Salvucci, Michael E. (2002). "RUBISCO: Structure, Regulatory Interactions, and Possibilities for a Better Enzyme". Annual Review of Plant Biology. 53: 449–475. doi:10.1146/annurev.arplant.53.100301.135233. PMID 12221984.
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