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Estradiol hemisuccinate (brand name Eutocol), or simply estradiol succinate, also known as estradiol 17β-hemisuccinate, is an estrogen medication and an estrogen ester – specifically, the hemisuccinate ester of estradiol.[1] It is used as a component of hormone replacement therapy for menopause.[2] Like other estrogens, estradiol hemisuccinate has been found to have beneficial effects on the skin, with improvement of skin thickness observed.[2][3]

Estradiol hemisuccinate is also a component of estradiol hemisuccinate/progesterone (brand name Hosterona), an injectable preparation used to induce withdrawal bleeding in women with amenorrhea.[4][5][6]

See also

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 897. ISBN 978-1-4757-2085-3.
  2. ^ a b Thompson Z, Maibach HI (2010). "Biological Effects of Estrogen on Skin". In Farage MA, Miller KW (eds.). Textbook of Aging Skin. pp. 361–367 (362). doi:10.1007/978-3-540-89656-2_35. ISBN 978-3-540-89655-5.
  3. ^ Maheux R, Naud F, Rioux M, Grenier R, Lemay A, Guy J, Langevin M (February 1994). "A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness". American Journal of Obstetrics and Gynecology. 170 (2): 642–649. doi:10.1016/s0002-9378(94)70242-x. PMID 8116726.
  4. ^ "¿Qué es Hosterona y para qué sirve?" [What is Hosterona and what is it for?]. matchmyrx.com (in Spanish). PRX Control Solutions. Archived from the original on 13 April 2019.
  5. ^ "Hosterona - Para qué sirve" [Hosterona - What it is for]. Los Medicamentos (in Spanish). 23 November 2012.
  6. ^ "HOSTERONA (Hormonoterapia)". Laboratorio GADOR.
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