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24-Methylenelophenol, or Gramisterol, also called 4α-Methyl-5α-ergosta-7,24(28)-dien-3β-ol is a Metabolic intermediate of sterol biosynthesis of plants and fungis,[1] can be converted from 4α-Methylfecosterol by enzyme HYD1 and converted to (Z)-24-ethylidenelophenol by 24-methylenesterol C-methyltransferase.[2]

References

  1. ^ Ullah, H; Khan, A; Rehman, NU; Halim, SA; Khan, H; Khan, I; Csuk, R; Al-Rawahi, A; Al-Hatmi, S; Al-Harrasi, A (24 April 2020). "Lophenol and lathosterol from resin of Commiphora kua possess hepatoprotective effects in vivo". Journal of Ethnopharmacology. 252: 112558. doi:10.1016/j.jep.2020.112558. PMID 31926985. S2CID 210166705.
  2. ^ Kuchta, T; Bartková, K; Kubinec, R (30 November 1992). "Ergosterol depletion and 4-methyl sterols accumulation in the yeast Saccharomyces cerevisiae treated with an antifungal, 6-amino-2-n-pentylthiobenzothiazole". Biochemical and Biophysical Research Communications. 189 (1): 85–91. doi:10.1016/0006-291x(92)91529-y. PMID 1449509.
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