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Alalevonadifloxacin (trade name Emrok O) is an antibiotic of the fluoroquinolone class.[1] It is a prodrug of levonadifloxacin with increased oral bioavailability.[2] In India, it is approved for the treatment of infections with Gram-positive bacteria.[3]

References

  1. ^ Saseedharan S, Dubey D, Singh RK, Zirpe K, Choudhuri AH, Mukherjee DN, et al. (2024). "Treatment challenges in the management of difficult-to-treat gram-positive infections: A consensus view apropos therapeutic role of novel anti-MRSA antibiotics, levonadifloxacin (IV) and alalevonadifloxacin (oral)". Indian Journal of Medical Microbiology. 47: 100528. doi:10.1016/j.ijmmb.2024.100528. PMID 38228227.
  2. ^ Bhawsar S, Kale R, Deshpande P, Yeole R, Bhagwat S, Patel M (December 2021). "Design and synthesis of an oral prodrug alalevonadifloxacin for the treatment of MRSA infection". Bioorganic & Medicinal Chemistry Letters. 54: 128432. doi:10.1016/j.bmcl.2021.128432. PMID 34757217.
  3. ^ "Alalevonadifloxacin". AdisInsight. Springer Nature Switzerland AG.
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