It was patented in 1943 and came into medical use in 1949.[4]
It was marketed under the names Histadyl, Histalon, Neo-Antergan, Neo-Pyramine, and Nisaval.[5] In the 1960s and 70s it was a very common component in over-the-counter sleep aids such as "Alva-Tranquil", "Dormin", "Sedacaps", "Sominex", "Nytol", and many others.[5]
It is used in over-the-counter combination products to treat the common cold and menstrual symptoms such as Midol Complete.[6] It is also the active ingredient of the topical antihistamine creams Anthisan[7] and Neoantergan[1] sold for the treatment of insect bites, stings, and nettle rash.
^ abThornton, William E. (1 September 1977). "Sleep aids and sedatives". Journal of the American College of Emergency Physicians. 6 (9): 408–412. doi:10.1016/S0361-1124(77)80006-3.
Recent Comments