Zinc finger protein 197 is a protein that in humans is encoded by the ZNF197 gene. [3]

Function

This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Naturally-occurring readthrough transcription is observed between this gene and the upstream zinc finger protein 660 gene and is represented by GeneID:110354863.

References

  1. ^ a b c ENSG00000186448 GRCh38: Ensembl release 89: ENSG00000281709, ENSG00000186448 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: Zinc finger protein 197". Retrieved 2017-07-06.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.