Zinc finger and BTB domain containing 1 is a protein in humans that is encoded by the ZBTB1 gene.[5]

ZBTB1 is essential for the development of lymphocytes in mice: T cells are absent from ZBTB1 mutant mice, and numbers of B cells and natural killer cells are reduced.[6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000126804 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033454 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zinc finger and BTB domain containing 1".
  6. ^ Siggs OM, Li X, Xia Y, Beutler B (January 2012). "ZBTB1 is a determinant of lymphoid development". The Journal of Experimental Medicine. 209 (1): 19–27. doi:10.1084/jem.20112084. PMC 3260866. PMID 22201126.
  7. ^ Punwani D, Simon K, Choi Y, Dutra A, Gonzalez-Espinosa D, Pak E, Naradikian M, Song CH, Zhang J, Bodine DM, Puck JM (August 2012). "Transcription factor zinc finger and BTB domain 1 is essential for lymphocyte development". Journal of Immunology. 189 (3): 1253–64. doi:10.4049/jimmunol.1200623. PMC 3401355. PMID 22753936.