Hosta

by | Mar 16, 2018 | Hosta

How Can We Help?
You are here:
< Back

VUF-6002 (JNJ-10191584) is a drug which acts as a potent and selective antagonist at the histamine H4 receptor.[1] It has anti-inflammatory and analgesic effects in animal studies of inflammatory diseases.[2]

See also

  • JNJ-7777120 (same molecule but where one nitrogen has been exchanged for a carbon)

References

  1. ^ Zhang M, Thurmond RL, Dunford PJ (March 2007). "The histamine H(4) receptor: a novel modulator of inflammatory and immune disorders". Pharmacology & Therapeutics. 113 (3): 594–606. doi:10.1016/j.pharmthera.2006.11.008. PMID 17275092.
  2. ^ Coruzzi G, Adami M, Guaita E, de Esch IJ, Leurs R (June 2007). "Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation". European Journal of Pharmacology. 563 (1–3): 240–4. doi:10.1016/j.ejphar.2007.02.026. PMID 17382315.
Categories
Table of Contents