Tripartite motif containing 34 is a protein that, in humans, is encoded by the TRIM34 gene.[3]

Function

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000258659 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: Tripartite motif containing 34". Retrieved 2016-09-01.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.