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Chemical compound
Sulfoxone or aldesulfone sodium is an anti-leprosy drug.[1] It is also known as diasone. Sulfoxone sodium was introduced in Japan in 1948.[2] Ernest Muir introduced it to Western use while serving as superintendent of the Chacachacare Leprosarium on Trinidad in the Caribbean.[3]
References
- ^ "Sulfoxone".
- ^ Ozawa H, Maruyama Y (2002). "[A 50-year history of new drugs in Japan: the developments of antileprosy drugs and their epidemiological aspects]". Yakushigaku Zasshi. 37 (1): 76–83. PMID 12412600.
- ^ Browne, Stanley George (1974), "Ernest Muir, C.M.G., C.I.E., M.D. (Edin.), F.R.C.S., LL.D. 1880–1974" (PDF), International Journal of Leprosy, vol. 42, no. 4, Bauru: International Leprosy Association, pp. 457–458, PMID 4617724.
Nucleic acid inhibitor |
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Protein synthesis inhibitor |
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Cell envelope antibiotic |
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Other/unknown | |||||||||
Combinations | |||||||||
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Antifolates (inhibit bacterial purine metabolism, thereby inhibiting DNA and RNA synthesis) |
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Quinolones (inhibit bacterial topoisomerase and/or DNA gyrase, thereby inhibiting DNA replication) |
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Anaerobic DNA inhibitors |
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RNA synthesis |
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