Sandra Saouaf is an American immunologist who researches autoimmune diseases, such as rheumatoid arthritis, type 1 diabetes, multiple sclerosis and others.
Biography
Sandra Jerrold-Jones obtained a BA from Rutgers College in biochemistry and went on to earn a PhD in immunology from the University of Pennsylvania.[1] After completion of her degree, Saouaf went to work in the cell signaling laboratory of Bristol-Myers Squibb[2][3] where she completed her post doctorate fellowship.[4] She then worked briefly at GlaxoSmithKline before returning to the University of Pennsylvania.[2] Saouaf left the university and began a consulting business with pharmaceutical and biotechnical companies,[2] hoping to help speed the process of discoveries for drugs to treat autoimmune disease. In 2012, together with University of Pennsylvania colleagues, she "discovered a possible treatment approach...through oral drugs" and founded Atlantic Bio Sci, LLC.[1] In 2013, she won a Fellowship from the Alliance of Women Entrepreneurs.[5]
Selected works
- Weiner, D B; Williams, W V; Siegel, R M; Jerrold-Jones, S; et al. (January 1989). "Molecular characterization of suppressor T cells". Transplantation Proceedings. 20 (6): 1151–1153. PMID 2974197.
- Siegel, Richard M; Katsumata, Makoto; Komori, Shinji; Jerrold-Jones, Sandra; et al. (December 1990). "Mechanisms of Autoimmunity in the Context of T-Cell Tolerance: Insights from Natural and Transgenic Animal Model Systems". Immunological Reviews. 118 (1): 165–192. doi:10.1111/j.1600-065X.1990.tb00816.x. PMID 2150401. S2CID 24544491.
- Saouaf, Sandra J; Mahajan, Sandeep; Rowley, R Bruce; Kut, Stephanie A; et al. (September 1994). "Temporal Differences in the Activation of Three Classes of Non-Transmembrane Protein Tyrosine Kinases Following B-Cell Antigen Receptor Surface Engagement". Proceedings of the National Academy of Sciences of the United States of America. 91 (20): 9524–9528. Bibcode:1994PNAS...91.9524S. doi:10.1073/pnas.91.20.9524. PMC 44845. PMID 7524079.
- Saouaf, Sandra J; Kut, Stephanie A; Fargnoli, Joseph; Rowley, R Bruce; et al. (1995). "Reconstitution of the B cell antigen receptor signaling components in COS cells". The Journal of Biological Chemistry. 270 (45): 27072–8. doi:10.1074/jbc.270.45.27072. PMID 7592958.
- Saouaf, Sandra J; Brennan, Patrick J; Shen, Yuan; Greene, Mark I. (December 2003). "Mechanisms of peripheral immune tolerance: Conversion of the immune to the unresponsive phenotype". Immunologic Research. 28 (3): 193–199. doi:10.1385/ir:28:3:193. PMID 14713714. S2CID 27480991.
- Iacono, Kathryn T.; Brown, Amy L.; Greene, Mark I.; Saouaf, Sandra J. (December 2007). "CD147 Immunoglobulin Superfamily Receptor Function and Role in Pathology". Experimental and Molecular Pathology. 83 (3): 283–295. doi:10.1016/j.yexmp.2007.08.014. PMC 2211739. PMID 17945211.
- Saouaf, Sandra J; Brennan, Patrick J; Shen, Yuan; Greene, Mark I. (October 2009). "Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis". Experimental and Molecular Pathology. 87 (2): 99–104. doi:10.1016/j.yexmp.2009.06.003. PMC 2753738. PMID 19577564.
References
- ^ a b Friedman, Sally (8 July 2014). "Moorestown doctor on crusade against common disorders". Courier Post. Retrieved 25 November 2015.
- ^ a b c "Women in STEM: Professional Advice for High School Students". Aston, Pennsylvania: Neumann University. 24 October 2014. Retrieved 25 November 2015.
- ^ Gupta, et al. 2013, p. 131.
- ^ "Sandra Saouaf". Connect6. Retrieved 25 November 2015.
- ^ "Meet Our 2013 Fellows". Pottstown, Pennsylvania: Alliance of Women Entrepreneurs. 2013. Retrieved 25 November 2015.
Bibliography
- Gupta, Sudhir; Paul, William E.; DeFranco, Anthony; Perlmutter, Roger (2013). Mechanisms of Lymphocyte Activation and Immune Regulation V: Molecular Basis of Signal Transduction. New York: Springer Science & Business Media. ISBN 978-1-4899-0987-9.
External links
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