Pyr-T (N,N-tetramethylenetryptamine) is a lesser-known, possible psychedelic drug. Pyr-T was first characterized by S. Mitzal.[1] Toxicity testing was later performed by Hunt and Brimblecombe, and although a lethal dosage was found in rats, a value is not given.[2] In the book TiHKAL (Tryptamines I Have Known and Loved), neither the dosage nor the duration are reported.[3][4]

Pyr-T produces few to no effects in humans, but some behavioral changes were observed in animal tests.[2] Very little data exists about the pharmacological properties, metabolism, and toxicity of pyr-T.

See also

References

  1. ^ Mitzal, S. (1962). "N/A". Dissertationes Pharm. 14: 305.
  2. ^ a b Hunt, R. R.; Brimblecombe, R. W. (July 1967). "Synthesis and Biological Activity of Some Ring-Substituted Tryptamines". Journal of Medicinal Chemistry. 10 (4): 646–648. doi:10.1021/jm00316a027. PMID 4962512.
  3. ^ Shulgin, Alexander; Shulgin, Ann (1997). TiHKAL, The Continuation (1st ed.). Berkeley, CA, USA: Transform Press. pp. 577–578. ISBN 0-9630096-9-9. Retrieved 7 April 2018.
  4. ^ Krasowski MD, Ekins S. Using cheminformatics to predict cross reactivity of “designer drugs” to their currently available immunoassays. J Cheminform 6, 22 (2014). doi:10.1186/1758-2946-6-22