Hosta

Picornain 2A (EC 3.4.22.29, picornavirus endopeptidase 2A, poliovirus protease 2A, rhinovirus protease 2A, 2A protease, 2A proteinase, protease 2A, proteinase 2Apro, picornaviral 2A proteinase, Y-G proteinase 2A, poliovirus proteinase 2A, poliovirus protease 2Apro) is a protease enzyme.^[1]^[2]^[3] This enzyme catalyses selective cleavage of Tyr-Gly bond in picornavirus polyprotein.

This enzyme is coded by entero-, rhino-, aphto- and cardioviruses.

References

^ Bazan JF, Fletterick RJ (November 1988). "Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications". Proceedings of the National Academy of Sciences of the United States of America. 85 (21): 7872–6. Bibcode:1988PNAS...85.7872B. doi:10.1073/pnas.85.21.7872. PMC 282299. PMID 3186696.
^ König H, Rosenwirth B (April 1988). "Purification and partial characterization of poliovirus protease 2A by means of a functional assay". Journal of Virology. 62 (4): 1243–50. doi:10.1128/JVI.62.4.1243-1250.1988. PMC 253133. PMID 2831385.
^ Kräusslich HG, Wimmer E (1988). "Viral proteinases". Annual Review of Biochemistry. 57: 701–54. doi:10.1146/annurev.bi.57.070188.003413. PMID 3052288.

External links

Picornain+2A at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[1] Bazan JF, Fletterick RJ (November 1988). "Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications". Proceedings of the National Academy of Sciences of the United States of America. 85 (21): 7872–6. Bibcode:1988PNAS...85.7872B. doi:10.1073/pnas.85.21.7872. PMC 282299. PMID 3186696.

[2] König H, Rosenwirth B (April 1988). "Purification and partial characterization of poliovirus protease 2A by means of a functional assay". Journal of Virology. 62 (4): 1243–50. doi:10.1128/JVI.62.4.1243-1250.1988. PMC 253133. PMID 2831385.

[3] Kräusslich HG, Wimmer E (1988). "Viral proteinases". Annual Review of Biochemistry. 57: 701–54. doi:10.1146/annurev.bi.57.070188.003413. PMID 3052288.

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[2]

[3]

Proteases: cysteine proteases (EC 3.4.22)
Caspase	Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase 13 Caspase 14
Fruit-derived	Papain Ficain Bromelain Actinidain
Calpain	CAPN1 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPNS1 CAPNS2
Cathepsin	B C F H K L1/L2 O S W Z
Other	Clostripain Cancer procoagulant Separase Autophagin Cruzipain 3C-like protease Gingipain R Gingipain K

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Hosta

References

External links

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