Physalis pruinosa is a plant in the genus Physalis in the nightshade family Solanaceae, often referred to as ground cherry or husk tomato. It is a native species in a range extending from northern Mexico through Central America.[1] The plant has a low, spreading habit, and fruits develop in a papery husk, as is characteristic of the genus. While most parts of the plant are toxic to humans due to the presence of solanine and solanidine,[2] the fruit becomes edible (and sweet) once it has ripened to yellow. (The papery husk, a calyx, remains toxic and should not be eaten.) The fruit's flavor is similar in some respects to that of a ripe tomatillo, but notably has a strong flavor of pineapple as well, a fact reflected in the name of a common commercial variety, "Cossack Pineapple". The ripe fruit of Physalis pruinosa var. argentina J. M. Toledo & Barboza is a food source for the Pilagá ethnic group.[3]

It is currently the subject of research into the possibility of developing a genetically modified variety for industrialized agriculture.[4] The research involves CRISPR genome editing which may be able to accelerate the domestication process.[5]

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