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Phosphoramidon is a chemical compound derived from cultures of Streptomyces tanashiensis. It is an inhibitor of the enzyme thermolysin,[2] of the membrane metallo-endopeptidase,[3] and of the endothelin converting enzyme.[3] Chemically, phosphoramidon differs from its closely related peptidase inhibitor talopeptin by a single stereocenter.
Because of its enzyme inhibitory properties, phosphoramidon is widely used as a biochemical tool.[citation needed]
References
- ^ a b Phosphoramidon, Enzo Life Sciences
- ^ Kitagishi K, Hiromi K (1984). "Binding between thermolysin and its specific inhibitor, phosphoramidon". Journal of Biochemistry. 95 (2): 529–34. PMID 6715312.
- ^ a b Phosphoramidon at PubChem
External links
- The MEROPS online database for peptidases and their inhibitors: Phosphoramidon
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