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Panin (Russian: Па́нин), or Panina (feminine; Па́нина) is a Russian surname.

"Panin" may refer to:

• Members of a noble Panin family
  • Count Nikita Ivanovich Panin
  • Count Petr Ivanovich Panin
  • Count Nikita Petrovich Panin
  • Count Alexander Panin
  • Count Viktor Nikitich Panin, a Russian statesman
  • General Count Petr Ivanovich Panin
  • Count Gerard Panin
• Adam Panin
• Aleksei Panin (born 1977), Russian actor
• Andrey Panin (1962–2013), Russian actor and director
• Boris Panin (1848–1917), Prime Minister
• Gennady Panin (born 1981), Russian politician
• Ivan Panin (1855–1942)
• Ivan Panin (mathematician) (born 1959), Russian mathematician
• Nikita Fyodorovich Panin († 1652)
• Nikolai Panin (1872–1956), Russian figure skater and Olympic champion
• Pavel Panin [ru] (1909–1943), a Soviet aircraft pilot and Hero of the Soviet Union
• Stepan Panin
• Vasily Panin

"Panina" may refer to:

• Countess Sofia Panina (1871–1956), philanthropist and Kadet Party politician
• Valentina Panina, a Russian actress.
• Varya Panina (Varvara Panina, Varja Panina), (1872 – May 28, 1911), A famous Russian Gypsy romance singer of the beginning of the 20th century
• Several people called Natalya Panina