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PHD finger protein 2 is a protein that in humans is encoded by the PHF2 gene.[5]
Function
This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000197724 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038025 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: PHD finger protein 2". Retrieved 2016-04-09.
Further reading
- Sinha S, Singh RK, Alam N, Roy A, Roychoudhury S, Panda CK (2008). "Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: pathological significance in early- and late-onset breast carcinoma". Mol. Cancer. 7: 84. doi:10.1186/1476-4598-7-84. PMC 2633285. PMID 18990233.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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