OTU deubiquitinase 1 is a protein that in humans is encoded by the OTUD1 gene. [5]

Function

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165312 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043415 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: OTU deubiquitinase 1". Retrieved 2016-03-13.

External links

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human OTU domain-containing protein 1

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.