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Chemical compound
Naloxonazine is a potent, irreversible μ-opioid receptor antagonist.[1] Naloxonazine forms spontaneously in acidic solutions of naloxazone, and may be responsible for much or all of the irreversible μ opioid receptor binding displayed by the latter.[2]
See also
- Oxymorphone-3-methoxynaltrexonazine, a similar opioid also having two complete and mirrored morphinan carbon skeletons
References
- ^ Naloxonazine dihydrochloride
- ^ Hahn, E. F.; Pasternak, G. W. (September 1982). "Naloxonazine, a potent, long-lasting inhibitor of opiate binding sites". Life Sciences. 31 (12–13): 1385–1388. doi:10.1016/0024-3205(82)90387-3. PMID 6292633.
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