Hosta

In enzymology, a N-carbamoyl-D-amino acid hydrolase (EC 3.5.1.77) is an enzyme that catalyzes the chemical reaction

N-carbamoyl-D-amino acid + H₂O D-amino acid + NH₃ + CO₂

Thus, the two substrates of this enzyme are N-carbamoyl-D-amino acid and H₂O, whereas its 3 products are D-amino acid, NH₃, and CO₂.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1ERZ, 1UF4, 1UF5, 1UF7, 1UF8, 2GGK, and 2GGL.

References

• Ogawa J, Shimizu S, Yamada H (1993). "N-carbamoyl-D-amino acid amidohydrolase from Comamonas sp. E222c purification and characterization". Eur. J. Biochem. 212 (3): 685–91. doi:10.1111/j.1432-1033.1993.tb17706.x. PMID 8462543.