Hosta

The enzyme multiple inositol-polyphosphate phosphatase (EC 3.1.3.62) catalyzes the reaction

myo-inositol hexakisphosphate + H₂O myo-inositol pentakisphosphate (mixed isomers) + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is 1D-myo-inositol-hexakisphosphate 5-phosphohydrolase. Other names in common use include inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase, inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase, inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase, inositol tetrakisphosphate phosphomonoesterase, inositol-1,3,4,5-tetrakisphosphate 3-phosphatase, and MIPP. This enzyme participates in inositol phosphate metabolism.

References

• Cullen PJ, Irvine RF, Drobak BK, Dawson AP (1989). "Inositol 1,3,4,5-tetrakisphosphate causes release of Ca²⁺ from permeabilized mouse lymphoma L1210 cells by its conversion into inositol 1,4,5-trisphosphate". Biochem. J. 259 (3): 931–3. PMC 1138610. PMID 2786415.
• Craxton A, Caffrey JJ, Burkhart W, Safrany ST, Shears SB. "Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphatase". Biochem. J. 328: 75–81. PMC 1218889. PMID 9359836.