MORC family CW-type zinc finger 1 is a protein that in humans is encoded by the MORC1 gene.[5]

Function

This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells. [provided by RefSeq, Jan 2009].

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000114487 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022652 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: MORC family CW-type zinc finger 1". Retrieved 2018-07-12.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.