Cysteine methyl ester is the organic compound with the formula HSCH2CH(NH2)CO2CH3. A white solid, it is the methyl ester of the amino acid cysteine.

Uses

Under the brand name Mecysteine, cysteine methyl ester is a commercial drug with mucolytic activity.[1] It is used as mucolytic and fluidifying for chronic and acute respiratory disorders. The drug is sold under the commercial names Delta in Paraguay, and Pectite and Zeotin in Japan.[2]

Cysteine methyl ester is also used as a building block for synthesis of N,S-heterocycles.[3][4]

References

  1. ^ Page CP (2018). "Respiratory System: Mucolytics". In Datta ST, Xiu P (eds.). Pharmacology (Fifth ed.). Philadelphia, PA: Elsevier. p. 40. ISBN 978-0-7020-7345-8.
  2. ^ "Mecysteine". Drugs.com.
  3. ^ Tanaka T, Nakashima T, Ueda T, Tomii K, Kouno I (June 2007). "Facile discrimination of aldose enantiomers by reversed-phase HPLC". Chemical & Pharmaceutical Bulletin. 55 (6): 899–901. doi:10.1248/cpb.55.899. hdl:10069/14910. PMID 17541189.
  4. ^ Hamada Y, Shibata M, Sugiura T, Kato S, Shioiri T (1987). "New methods and reagents in organic synthesis. 67. A general synthesis of derivatives of optically pure 2-(1-aminoalkyl)thiazole-4-carboxylic acids". The Journal of Organic Chemistry. 52 (7): 1252–1255. doi:10.1021/jo00383a014.