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Mannosylglycerate hydrolase (EC 3.2.1.170, 2-O-(6-phospho-mannosyl)-D-glycerate hydrolase, alpha-mannosidase, mngB (gene)) is an enzyme with systematic name 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate acylhydrolase.[1] This enzyme catalyses the following chemical reaction

2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate + H2O D-mannose 6-phosphate + D-glycerate

The enzyme participates in the mannosylglycerate degradation pathway of some bacteria.

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