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The enzyme mannitol-1-phosphatase (EC 3.1.3.22) catalyzes the reaction

D-mannitol 1-phosphate + H2O D-mannitol + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is D-mannitol-1-phosphate phosphohydrolase. This enzyme is also called mannitol-1-phosphate phosphatase. This enzyme participates in fructose and mannose metabolism.

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