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LIM homeobox 9 is a protein that in humans is encoded by the LHX9 gene.[5]
Function
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000143355 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019230 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: LIM homeobox 9".
Further reading
- Avraham O, Hadas Y, Vald L, Zisman S, Schejter A, Visel A, Klar A (2009). "Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1". Neural Dev. 4: 21. doi:10.1186/1749-8104-4-21. PMC 2704203. PMID 19545367.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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