Leptosidin was the first aurone to be isolated in Coreopsis grandiflora by Geissman T.A. and Heaton C.D. in 1943.[1] Leptosidin blocks the active residues of PRKACA.[2]

References

  1. ^ Leptosidin on metabolomics.jp
  2. ^ S, Sandeep; V, Priyadarshini; D, Pradhan; M, Munikumar; A, Umamaheswari (2012). "Docking and molecular dynamics simulations studies of human protein kinase catalytic subunit alpha with antagonist". Journal of Clinical and Scientific Research: 15–23. doi:10.15380/2277-5706.JCSR.12.005.