Interiotherins A-C

Interiotherins are lignans isolated from Kadsura.[1][2]

They have a core of dibenzocyclooctadiene and contain methyl and methoxy side chains.[3] They have a role as anti-HIV agent.[4]

References

  1. ^ Chen DF, Zhang SX, Kozuka M, et al. (September 2002). "Interiotherins C and D, two new lignans from Kadsura interior and antitumor-promoting effects of related neolignans on Epstein-Barr virus activation". Journal of Natural Products. 65 (9): 1242–5. doi:10.1021/np0105127. PMID 12350139.
  2. ^ Chen DF, Zhang SX, Chen K, et al. (November 1996). "Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior". Journal of Natural Products. 59 (11): 1066–8. doi:10.1021/np9601667. PMID 8946749.
  3. ^ Coleman, Robert S.; Gurrala, Srinivas Reddy (1 April 2005). "Asymmetric Synthesis of the Dibenzocyclooctadiene Lignans Interiotherin A and Gomisin R". Organic Letters. 7 (9): 1849–1852. doi:10.1021/ol050476t.
  4. ^ PubChem. "Interiotherin A". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-09-22.