High Desert Regional Medical Center, also known as HDRHC, or by the name High Desert Regional, is a 142,000-square-foot ambulatory care clinic located at 335 East Avenue I in the Lancaster, California[1] It is operated by the Los Angeles County Department of Health Services through its Ambulatory Care Network (ACN).

The medical facility was awarded the 2015 DBIA National Design-Build Project/Team Award in the healthcare facility category.[2] Artist Brad Howe was commissioned to design a sculpture titled "One Desert Sky" that hangs over the lobby of the facility.[3]

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