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The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B. Mutations in this family have been found to cause a blockage in RNA replication and it is thought that both the primary sequence and the structure of this element are crucial for HCV RNA replication.[1]
See also
- Hepatitis C alternative reading frame stem-loop
- Hepatitis C virus 3'X element
- Hepatitis C virus stem-loop VII
- Hepatitis C stem-loop IV
- Hepatitis C
References
- ^ You S, Stump DD, Branch AD, Rice CM (February 2004). "A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication". Journal of Virology. 78 (3): 1352–1366. doi:10.1128/JVI.78.3.1352-1366.2004. PMC 321395. PMID 14722290.
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