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Summary
DescriptionSubhash nucleoid 06.png |
English: Twin supercoiling domain model for transcription-induced supercoiling A. An example of topologically constrained DNA. A grey bar represents a topological constraint, e.g. a protein or a membrane anchor. B. Accommodation of RNA polymerase for transcription initiation results in the opening of the DNA double helix. C. An elongating RNA polymerase complex cannot rotate around the helical axis of DNA. Therefore, removal of helical turns by RNA polymerase causes overwinding of the topologically constrained DNA ahead and underwinding of the DNA behind, generating positively and negatively supercoiled DNA, respectively. Supercoiling can manifest as either change in the numbers of twists as shown in C or plectonemic writhe as shown in D. |
Date | |
Source | doi:10.1371/journal.pgen.1008456 Verma SC, Qian Z, Adhya SL (2019) Architecture of the Escherichia coli nucleoid. PLoS Genet 15(12): e1008456. |
Author | Subhash C. Verma, Zhong Qian, Sankar L. Adhya |
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12 December 2019
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current | 00:15, 18 December 2019 | 2,260 × 3,089 (412 KB) | Evolution and evolvability | User created page with UploadWizard |
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Width | 2,260 px |
Height | 3,089 px |
Pixel composition | RGB |
Number of components | 3 |
Horizontal resolution | 400 dpi |
Vertical resolution | 400 dpi |
Color space | sRGB |
Image width | 2,260 px |
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Software used | Adobe Photoshop CC 2018 (Macintosh) |
Date and time of digitizing | 08:12, 5 April 2019 |
File change date and time | 11:58, 5 April 2019 |
Date metadata was last modified | 11:58, 5 April 2019 |
Unique ID of original document | uuid:9E3E5C9A8C81DB118734DB58FDDE4BA7 |
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