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Chemical compound
This article is about a non-clinically used compound. For the pharmaceutical drug, see Estramustine phosphate.
Estramustine (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name, BANTooltip British Approved Name) is an estrogen and cytostatic antineoplastic agent which was never marketed.[1][2] It is an estrogen ester – specifically, the C3 normustine ester of estradiol – and acts in part as a prodrug of estradiol in the body.[1][2] Estramustine phosphate, the C17β phosphate ester of estramustine and a prodrug of estramustine, estromustine, estradiol, and estrone, is marketed and used in the treatment of prostate cancer.[1][2]
See also
- Estradiol mustard
- List of hormonal cytostatic antineoplastic agents
- List of estrogen esters § Estradiol esters
References
- ^ a b c Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 502–. ISBN 978-1-4757-2085-3.
- ^ a b c Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 406–. ISBN 978-3-88763-075-1.
ERTooltip Estrogen receptor |
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GPERTooltip G protein-coupled estrogen receptor |
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ARTooltip Androgen receptor |
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GPRC6A |
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