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Monoclonal antibody
Emibetuzumab (INN[1]) (LY2875358) is a humanized monoclonal antibody designed for the treatment of cancer.[2] It is in phase II trials for patients with NSCLC[3]
This drug was developed by Eli Lilly & Company.
References
- ^ World Health Organization (2014). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 111" (PDF). WHO Drug Information. 28 (2).
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Emibetuzumab, American Medical Association.
- ^ Camidge DR, Moran T, Demedts I, Grosch H, Di Mercurio JP, Mileham KF, et al. "A randomized, open-label, phase 2 study of emibetuzumab plus erlotinib (LY+E) and emibetuzumab monotherapy (LY) in patients with acquired resistance to erlotinib and MET diagnostic positive (MET Dx+) metastatic NSCLC".
Angiopoietin |
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CNTF |
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EGF (ErbB) |
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FGF |
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HGF (c-Met) |
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IGF |
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LNGF (p75NTR) |
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PDGF |
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RET (GFL) |
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SCF (c-Kit) |
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TGFβ |
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Trk |
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VEGF |
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Others |
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