Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D.[1]

References

  1. ^ Gagnon R, Ogden GW, Just G, Kaye M (April 1974). "Comparison of dihydrotachysterol and 5,6-trans vitamin D3 on intestinal calcium absorption in patients with chronic renal failure". Canadian Journal of Physiology and Pharmacology. 52 (2): 272–4. doi:10.1139/y74-037. PMID 4365509.