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Dessa is an American singer, rapper, and writer.

Dessa may also refer to:

• Dessa, Niger, a village and rural commune
• Dessa (artist), Swiss visual artist Deborah Petroz-Abeles (born 1948)
• Dessa (Filipina singer), Filipino singer Maria Destreza Alivio Salazar (born 1974)
• the title character of Dessa Rose, a novel by Sherley Anne Williams
• Dessa Rose (musical), a musical based on the novel
• Dessa, a fictitious planet in the Soviet film Per Aspera Ad Astra