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Department of Scientific and Industrial Research, abbreviated DSIR was the name of several British Empire organisations founded after the 1923 Imperial Conference to foster intra-Empire trade and development.

• Department of Scientific and Industrial Research (United Kingdom), a department of the British Government responsible for the organisation, development and encouragement of scientific and industrial research
• Department of Scientific and Industrial Research (New Zealand), a now-defunct government science agency in New Zealand, founded in 1926 and broken into Crown Research Institutes in 1992
• Department of Scientific and Industrial Research (India)

See also

• Commonwealth Scientific and Industrial Research Organisation the parallel organisation in Australia