Deacetylasperulosidic acid is an iridoid compound found in a few medicinal plants, such as Morinda citrifolia.[1] Some in vitro and in vivo bioactivities of deacetylasperulosidic acid include anti-inflammatory, analgesic, anti-cancer, antioxidant, anti-arthritic, anti-mutagenic, anti-clastogenic, and hepatoprotection.[2][3][4][5][6]

References

  1. ^ Potterat O, Von Felten R, Dalsgaard PW, Hamburger M (2007). "Identification of TLC markers and quantification by HPLC-MS of various constituents in noni fruit powder and commercial noni-derived products". J. Agric. Food Chem. 55 (18): 7489–7494. doi:10.1021/jf071359a. PMID 17696360.
  2. ^ Akihisa, T; Matsumoto, K; Tokuda, H; Yasukawa, K; Seino, K; Nakamoto, K; Kuninaga, H; Suzuki, T; Kimura, Y (2007). "Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni)". Journal of Natural Products. 70 (5): 754–7. doi:10.1021/np068065o. PMID 17480098.
  3. ^ Liu, G; Bode, A; Ma, WY; Sang, S; Ho, CT; Dong, Z (2001). "Two novel glycosides from the fruits of Morinda citrifolia (noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line". Cancer Research. 61 (15): 5749–56. PMID 11479211.
  4. ^ Ling, SK; Tanaka, T; Kouno, I (2003). "Effects of iridoids on lipoxygenase and hyaluronidase activities and their activation by beta-glucosidase in the presence of amino acids" (PDF). Biological & Pharmaceutical Bulletin. 26 (3): 352–6. doi:10.1248/bpb.26.352. PMID 12612446.
  5. ^ Kim DH, Lee HJ, Oh YJ, Kim MJ, Kim SH, Jeong TS, Baek NI (2005). "Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-oxidation". Arch Pharm Res. 28 (10): 1156–1160. doi:10.1007/BF02972979. PMID 16276972. S2CID 11924214.
  6. ^ Nakamura, T; Nakazawa, Y; Onizuka, S; Satoh, S; Chiba, A; Sekihashi, K; Miura, A; Yasugahira, N; Sasaki, YF (1997). "Antimutagenicity of Tochu tea (an aqueous extract of Eucommia ulmoides leaves): 1. The clastogen-suppressing effects of Tochu tea in CHO cells and mice". Mutation Research. 388 (1): 7–20. doi:10.1016/s1383-5718(96)00096-4. PMID 9025787.