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CUGBP Elav-like family member 6 is a protein that in humans is encoded by the CELF6 gene. [2]
Function
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010].
References
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: CUGBP Elav-like family member 6". Retrieved 2018-04-18.
Further reading
- Ladd AN, Nguyen NH, Malhotra K, Cooper TA (April 2004). "CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing". J. Biol. Chem. 279 (17): 17756–64. doi:10.1074/jbc.M310687200. PMID 14761971.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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